At The Longevity Centers, we are pioneering a paradigm shift in how we approach aging and vitality. Rather than accepting decline as inevitable, we employ cutting-edge interventions that target the biological foundations of longevity. Among our most transformative offerings is EBOOST™—an advanced blood optimization therapy designed to improve conditions that promote both longevity and quality of life.
What Is EBOOST™ for Longevity?
EBOOST™ is our proprietary approach to EBOO, which stands for “Extracorporeal Blood Oxygenation and Ozonation.” This is a sophisticated therapy that fundamentally rejuvenates your circulatory system at the cellular level by delivering concentrated levels of ozone to the blood.1
Ozone is a gas consisting of three oxygen atoms. It exists naturally in the Earth’s atmosphere, playing an important UV-radiation-absorbing role that makes life on the planet possible.2EBOO (and EBOOSTTM) uses medical-grade ozone to increase the amount of oxygen in the body. This can have many therapeutic benefits.
The EBOOST™ Rejuvenation Process
Each EBOOST™ session involves a multi-stage blood transformation process. As your blood flows through our customized system, it first undergoes advanced filtration to eliminate accumulated cellular debris and inflammatory compounds.
Next, your blood receives an infusion of pharmaceutical-grade and precisely measured ozone. Following this, the blood passes through ultraviolet light exposure, which neutralizes pathogens and damaged cellular material, before being reintroduced to your system in its revitalized state.3
Unlike conventional IV therapies that simply introduce substances into your bloodstream, EBOOST™ performs a complete blood renewal process. Through a completely sealed, medical-grade system, your blood exits through one IV access point, undergoes multiple revitalization stages in our specialized equipment, and returns through a second line—all without ever breaking sterility.
What Sets Our Approach Apart
The true innovation of EBOOST™ lies in Dr. Kosubevsky’s custom engineering of our treatment system. Rather than following rigid, one-size-fits-all protocols typical of standard IV therapies, we calibrate each session to your unique physiology and longevity objectives.
During a typical 50-minute treatment, we process multiple liters of blood through repeated cycles. This means we can effectively renew most of your blood volume in a single appointment (the exact volume processed depends on the individualized parameters we establish for your treatment).
The Longevity Science of IV Ozone Therapy
While many wellness treatments focus on symptom relief, EBOOST™ operates at the fundamental level where aging begins: your cellular environment. Medical-grade ozone is an activated oxygen molecule that, when carefully introduced to blood under clinical conditions, can help initiate a powerful cascade of age-protective biological responses.
The dynamic centers on hormetic stress. When blood encounters calibrated amounts of medical ozone, it can: increase production of endogenous antioxidants, optimize immune surveillance, enhance microcirculation, and improve cellular resilience against oxidative damage.4
In short, added ozone can help prompt your cells to strengthen their defenses and enhance their function. This principle, which is currently being studied widely in the field of immunology, is at the forefront of longevity discovery.5
The filtration aspect of EBOOST™ is equally crucial for longevity. By physically extracting inflammatory mediators, cellular waste products, and accumulated toxins, we can potentially reduce the cumulative burden that accelerates aging. Combined with oxygenation, the result is blood that is purified, oxygen-enriched, and optimized for cellular longevity.
Longevity Benefits of EBOOSTTM
Oxygen is the cornerstone of energy production in every living cell. Just as replacing contaminated fluids restores peak performance to machinery, cleansing and super-oxygenating your blood at this foundational level gives every organ system the opportunity to function closer to its youthful potential.
Specifically, the IV ozone therapy benefits for longevity stem from how it supports your body’s core systems:
- Modulates chronic inflammation—the underlying driver of virtually all age-related diseases6
- Enhances immune precision, helping your body distinguish threats from healthy tissue
- Optimizes oxygen transport, ensuring every cell receives the fuel it needs for proper function
- Reduces toxic burden from environmental exposures, infections, and metabolic byproducts that accumulate over decades
Many of our patients arrive feeling trapped by premature aging—experiencing declining energy, cognitive cloudiness, and loss of resilience, despite maintaining healthy lifestyles. IV ozone therapy can help address what is happening beneath the surface at the mitochondrial and cellular level.
Following their treatment series, patients consistently describe experiencing a restoration of youthful vitality. Patients describe experiencing:
- Sustained energy throughout the day
- Mental sharpness they have not felt in years
- Enhanced physical stamina
- Noticeable reduction in the inflammatory burden (which was aging them prematurely)
Why Choose LCOA
What Sets Longevity Centers of America Apart?
- Personalized protocols tailored to your unique health goals
- Physician-led team with advanced training in functional and longevity medicine
- In-depth testing and root-cause diagnostics
- Concierge-level care and long-term support
- Proven therapies backed by science
- A calm, comfortable, and discreet environment
Who Can Benefit From EBOOST™?
At The Longevity Centers, we have witnessed profound rejuvenation in a diverse patient population. Anyone can benefit from EBOOST™, but ideal candidates may include adults focused on:
- Reversing biological aging markers and extending healthspan
- Resolving persistent inflammatory conditions that conventional medicine has failed to adequately address
- Recovering from chronic infections, including long COVID, Lyme disease, or other post-infectious syndromes
- Eliminating brain fog and fatigue that diminishes quality of life
- Optimizing immune function, especially in cases of autoimmune patterns or immune senescence
- Improving cardiovascular health and microcirculation
- Detoxifying from years of environmental toxins that accelerate aging
- Maximizing performance and recovery for executives and athletes committed to longevity
You do not need to be experiencing decline to benefit from EBOOST™. Many of our patients integrate this therapy as a preventive longevity strategy—investing in their healthspan before deterioration occurs. In longevity medicine, prevention and optimization are far more effective than intervention after damage accumulates.
Your EBOOST™ Longevity Experience
Your journey with EBOOST™ begins with a comprehensive longevity-focused consultation at The Longevity Centers. We will explore your health history, assess your biological age markers, and establish longevity objectives. Our specialized team will analyze your profile to design treatment parameters.
During EBOOST™ treatment, you will recline comfortably in our dedicated treatment suite. We establish two IV access points—one for blood outflow and one for return. Most patients use this time to read, practice meditation, or simply rest. The experience is reported by patients to be quite comfortable.
The requisite number of EBOOST™ sessions varies based on individual longevity goals and baseline health status. Some patients complete an intensive initial series to achieve a biological reset, while others incorporate regular maintenance sessions as part of their long-term longevity protocol. We will work with you to design a treatment strategy aligned with your schedule and personal health goals.
Frequently Asked Questions About IV Ozone Therapy
What is the difference between EBOOST™ and other IV therapies?
Unlike standard IV therapies that simply infuse nutrients or medications into your bloodstream, EBOOST™ is an advanced form of EBOO (Extracorporeal Blood Oxygenation and Ozonation) that actually processes your blood outside your body. Your blood is drawn through one IV line, filtered to remove toxins and inflammatory compounds, treated with medical-grade oxygen and ozone, exposed to UV light for pathogen neutralization, and then returned through another IV line.
How long does it take to see results from IV ozone therapy?
Many patients report noticeable improvements in energy, mental clarity, and overall vitality within 24 hours after their first IV ozone therapy session. However, the most profound IV ozone therapy benefits typically emerge over a series of treatments, as your body’s cellular systems undergo progressive rejuvenation. Some patients experience immediate relief from brain fog and fatigue, while deeper benefits like reduced inflammation, enhanced immune function, and improved cardiovascular health develop over several weeks.
Is IV ozone therapy safe?
IV ozone therapy has been used internationally for over 100 years with an excellent safety profile when administered by properly trained practitioners.7 At The Longevity Centers, we follow rigorous medical protocols, use only medical-grade equipment, maintain strict sterile technique, and carefully screen each patient to ensure EBOOST™ is appropriate for them. Dr. Kosubevsky’s extensive training and experience in advanced IV ozone therapy protocols ensure you receive the highest standard of care.
How many EBOOST™ sessions will I need?
The number of EBOOST™ sessions varies based on your individual health status and longevity objectives. Some patients benefit from an initial intensive series of three to six treatments over several weeks to achieve a biological reset, while others incorporate monthly or quarterly maintenance sessions as part of their ongoing longevity protocol.
References
- Robert Jay Rowen, Sharon Grabovac, and Teresa B. Su, “Ozone dialysis delivers three or more times the ozone than other forms of ozone blood treatment,” Medical Gas Research, September 2022, https://pmc.ncbi.nlm.nih.gov/articles/PMC9555023/.
- “Ozone Science,” United Nations, retrieved on February 5, 2026, from: https://www.un.org/en/observances/ozone-day/science.
- Ali Rezaie, Gabriela G. S. Leite, Gil Y. Melmed, et al., “Ultraviolet A light effectively reduces bacteria and viruses including coronavirus,” PLoS One, July 2020, https://pmc.ncbi.nlm.nih.gov/articles/PMC7365468/.
- Catia Scassellati, Antonio Carlo Galoforo, Cristian Bonvicini, et al, “Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders,” Ageing Research Reviews, August 2020, https://pmc.ncbi.nlm.nih.gov/articles/PMC7428719/.
- Katarzyna Napiórkowska-Baran, Jozef Slawatycki, Paula Klemenska, et al., “Ozone as an Immunomodulator—New Therapeutic Possibilities in the Treatment of Immunodeficiencies—A Narrative Review,” Current Issues in Molecular Biology, December 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC12731440/.
- Brown University Health Blog Team, “Inflammaging: What You Should Know About Inflammation and Aging,” Brown University Health, March 2024, https://www.brownhealth.org/be-well/inflammaging-what-you-should-know-about-inflammation-and-aging.
- Satya Lakshmi Komarraju, D. Sathyanath, Mandala Sathwik, and Shrikanth Muralidharan, “Historical Highlights of Ozone Therapy,” Journal of Pharmacy & BioAllied Sciences, September 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC12564041/.