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In the evolving landscape of integrative and functional medicine, few therapies generate as much excitement—and deliver as impressive results—as advanced IV ozone therapy. At The Longevity Centers of America, we are proud to offer EBOOSTTM, a state-of-the-art approach to blood revitalization that is helping our patients break through health plateaus and experience transformative improvements in how they feel, function, and thrive.

Understanding EBOOSTTM and IV Ozone Therapy

EBOOSTTM is a type of IV ozone therapy, of which there are many varieties. It is a version of “extracorporeal blood oxygenation and oxygenation” (EBOO) developed by The Longevity Center’s Dr. Benjamin Kosubevsky. This refers to a type of “ozone dialysis,” which entails oxygenating a large volume of blood outside the body. 

IV ozone therapy works by mixing medical-grade ozone gas with the patient’s blood, then reinfusing it. It is a form of major autohemotherapy (MAH), which is intended to stimulate the immune system by improving oxygenation and circulation, as well as reducing inflammation. 

Such therapies have been used to support different acute and chronic conditions, from fibromyalgia to wound healing and pain management. A recent study showed promising results in alleviating symptoms of “long COVID.”1 

What sets EBOOSTTM apart is its comprehensive, systemic approach to cleansing and optimizing your blood. This sophisticated therapy was developed in-house by our own Dr. Benjamin Kosubevsky, which means we are not locked into a standardized protocol. Instead, we can adjust parameters based on your unique biochemistry, health status, and therapeutic goals. 

EBOOSTTM involves a closed-circuit system where your blood is temporarily removed from your body via IV, processed through multiple beneficial stages, and then returned to you—all without ever being exposed to open air or contaminants. 

The goal is fourfold: 

  • Filtration to help remove cellular debris and inflammatory compounds
  • Oxygenation with medical-grade oxygen
  • Precise ozonation with carefully controlled amounts of therapeutic ozone
  • UV light exposure to help sterilize and deactivate pathogens

Throughout the therapy, we circulate substantial volumes of blood—often several liters over the course of the session. That means a large amount of blood volume passes through the system multiple times, depending on the specific parameters we set for your needs.

The Therapy Your Body Has Been Waiting For

Our patients consistently use one particular metaphor to describe their EBOOSTTM experience: it is like getting an oil change for your body. This comparison resonates because it captures exactly what we are attempting to accomplish with IV ozone therapy.

Consider what happens when you change your car’s oil. You drain out the old, contaminated fluid that has been collecting particles and losing effectiveness, replace it with clean, fresh oil, and suddenly your engine runs smoother, quieter, and more efficiently. EBOOSTTM can do something remarkably similar for your circulatory system.

The IV ozone therapy benefits we see at The Longevity Centers stem from this revitalization process. When your blood is filtered, oxygenated, and infused with precise amounts of medical ozone, your body can see several key advantages:

  • Reduced systemic inflammation that may be driving chronic symptoms
  • Enhanced immune function and better recognition of threats
  • Improved oxygen delivery to every cell and tissue
  • Decreased burden from accumulated toxins and microbes
  • Optimized cellular metabolism and energy production

Patients often tell us they notice differences they can feel in their daily lives. These include:

  • Sustained energy without the afternoon crash
  • Mental clarity and focus that had been missing for months or years
  • Reduced pain and inflammation in joints or muscles
  • Better sleep quality and more refreshing rest
  • Improved exercise tolerance and faster recovery times

The Biological Mechanisms Behind EBOOSTTM

To truly appreciate why IV ozone therapy creates such profound changes, it may help to understand what exactly is happening at a biological level. Medical ozone, when introduced to blood in controlled quantities, triggers a beneficial cascade of reactions.

Ozone is a molecule made of three oxygen atoms (O₃) rather than the usual two (O₂). This extra oxygen atom makes it highly reactive, and that reactivity is precisely what makes it therapeutic when used properly.2 When blood cells encounter medical ozone in our controlled environment, they often respond by:

  • Upregulating their antioxidant defense systems
  • Stimulating better oxygen utilization and metabolism
  • Activating immune cells to function more effectively
  • Improving the flexibility and flow characteristics of red blood cells

This principle—where a controlled, mild stressor triggers beneficial adaptive responses—is called hormesis, and it is one reason why IV therapies using ozone can have such impactful effects. Your body essentially gets a wake-up call that prompts it to function more efficiently across multiple systems.3

The filtration component of EBOOSTTM matters just as much. Your blood accumulates all sorts of debris over time—inflammatory proteins, damaged cell fragments, environmental toxins, microbial byproducts.4 Physically removing these substances can help lighten the load on your liver, kidneys, and lymphatic system, allowing them to function more effectively.

Who Should Consider IV Ozone Therapy?

At The Longevity Centers, we work with a diverse patient population, and EBOOSTTM serves many different health goals. The ideal candidates for IV ozone therapy typically fall into several categories.

  • We frequently see patients dealing with chronic inflammatory conditions that have not responded adequately to conventional treatments. Whether it is arthritis, cardiovascular inflammation, or mysterious inflammatory patterns without a clear diagnosis, the anti-inflammatory effects of IV ozone therapy may provide meaningful relief.
  • Many patients come to us experiencing the lingering aftermath of infections, such as those stemming from chronic Lyme disease, persistent post-viral symptoms (including “long COVID”), or recurring infections that suggest underlying immune dysfunction. The immune-modulating and antimicrobial properties of IV therapies like EBOOSTTM could have the potential to reset these patterns.
  • We see remarkable results in patients struggling with fatigue, brain fog, and cognitive challenges. Studies show that your blood is carrying more oxygen, delivering it more efficiently, and circulating with less inflammatory interference, your brain receives the support it desperately needs to function optimally.5

Additional conditions that may benefit from EBOOSTTM include:

  • Autoimmune conditions or immune dysregulation
  • Vascular or circulatory problems
  • Suspected toxic burden from environmental exposures or mold
  • High-performing individuals—athletes, executives, busy parents—who want to maintain peak performance and resilience
  • Metabolic syndrome or insulin resistance
  • Chronic pain syndromes
  • Cardiovascular disease or risk factors

Keep in mind that you do not need to be sick to benefit from EBOOSTTM. We also welcome patients who are feeling relatively well but want to invest proactively in their longevity and optimize their health trajectory. Prevention and maintenance are just as valuable as intervention.

Your EBOOSTTM Experience at The Longevity Centers

When you choose The Longevity Centers for IV ozone therapy, you are getting a comprehensive wellness partnership. Your journey begins with a detailed consultation where we will explore your health history, current symptoms, lifestyle factors, and what you are hoping to achieve.

patient receiving EBOOST therapy

We will review your case personally and design your EBOOSTTM protocol with settings optimized for your specific needs. For instance, some patients require more intensive filtration and higher ozone concentrations, while others may need gentler, more gradual approaches. This customization is one of our defining features.

What to expect during your session:

  • Pre-therapy assessment: We will check your vitals and ensure you are comfortable
  • IV placement: Two IV access points are established—one for blood exit and one for return
  • Session time: 50 minutes of comfortable relaxation
  • Activities: Bring work, read, listen to music, meditate, or simply rest
  • Post-therapy: Brief check-in and discussion of any immediate observations

How many sessions will you need? That depends entirely on your situation. Patients dealing with acute flares or specific events might do a short intensive series. Those managing chronic conditions often benefit from regular ongoing sessions—perhaps weekly initially, then spacing out to biweekly or monthly maintenance. We will create a recommendation based on how your body responds and what your health goals require.

Safety Standards and Patient Screening

IV ozone therapy has been utilized internationally for decades with an excellent safety record when performed by qualified practitioners using proper equipment and protocols.6 At The Longevity Centers, safety is non-negotiable.

Our safety protocols include:

  • Medical-grade ozone generators exclusively
  • Strict sterile technique 
  • Rigorous infection control protocols
  • Comprehensive patient screening before the first session
  • Ongoing monitoring 
  • Emergency protocols and trained staff

During your consultation, we will discuss your complete medical history, current medications, and any factors that might affect safety or efficacy. While IV ozone therapy benefits can be substantial for most appropriate candidates, there are some situations where other therapies might be more suitable. We will have honest conversations about what we believe will serve you best.

Begin Your EBOOSTTM Journey Today

If you are ready to experience what advanced IV therapy can do for your health, energy, and quality of life, The Longevity Centers are ready to welcome you. Whether you are managing chronic symptoms, recovering from illness, or optimizing for peak performance and longevity, IV ozone therapy may be exactly what your body needs.

If you have been searching for “IV ozone therapy near me,” you have found the right place. Our team is here to answer your questions, address your concerns, and guide you through every step of the process. Contact us today to schedule your consultation and discover how EBOOSTTM can transform your health story.


Frequently Asked Questions

How is EBOOSTTM different from other types of IV ozone therapy?

EBOOSTTM is a proprietary form of extracorporeal blood oxygenation and ozonation (EBOO) developed in-house by Dr. Benjamin Kosubevsky. Because the protocol was created at The Longevity Centers rather than adopted from a standardized template, parameters such as filtration intensity and ozone concentration can be adjusted to each patient’s biochemistry and therapeutic goals. The therapy also combines filtration, oxygenation, precise ozonation, and UV light exposure within a single closed-circuit session.

Is IV ozone therapy safe?

When performed by qualified practitioners using medical-grade equipment and proper protocols, IV ozone therapy has been used internationally for decades. At The Longevity Centers, every session follows strict sterile technique, rigorous infection-control standards, and ongoing monitoring, and each patient undergoes comprehensive screening beforehand. Your provider will review your complete medical history and current medications to help determine whether the therapy is appropriate for you.

Are there any side effects or downtime after a session?

Most patients tolerate EBOOSTTM well and are able to return to their normal activities afterward. Some may notice mild, temporary effects as the body responds to the therapy, which your care team will review during your consultation and post-session check-in. Because protocols are individualized, your provider can modify the intensity of future sessions as needed.

How soon might I notice results?

Responses vary from person to person and depend on individual health status and the goals being addressed. Some patients report improvements in energy, mental clarity, or sleep quality within a relatively short time, while others experience more gradual changes over a series of sessions. Your provider can help set realistic expectations based on your specific situation and how your body responds.

Can EBOOSTTM be combined with other therapies?

EBOOSTTM may be incorporated into a broader, individualized wellness plan alongside other therapies offered at The Longevity Centers. During your consultation, your care team can discuss how IV ozone might complement your existing therapies and overall health strategy.


References

  1. Yang He, Xu Liu, Shiqian Zha, et al., “A pilot randomized controlled trial of major ozone autohemotherapy for patients with post-acute sequelae of COVID-19,” International Immunopharmacology, September 2024, https://www.sciencedirect.com/science/article/abs/pii/S1567576924011949
  2. “Ozone,” Missouri State University, retrieved on January 7, 2025, from: https://www.missouristate.edu/Sustainability/ozone.htm
  3. Stephen C. Bondy, “The Hormesis Concept: Strengths and Shortcomings,” Biomolegulces, October 2023, https://pmc.ncbi.nlm.nih.gov/articles/PMC10604602/
  4. Umesh Chandra Dash, Nitish Kumar Bhol, Sandeep Kumar Swain, et al., “Oxidative stress and inflammation in the pathogenesis of neurological disorders: Mechanisms and implications,” Acta Pharmaceutica Sinica B, January 2025, https://www.sciencedirect.com/science/article/pii/S2211383524004040
  5. Qingguang Zhang, William D. Haselden, Serge Charpak, and Patrick J. Drew, “Could respiration-driven blood oxygen changes modulate neural activity?” European Journal of Physiology, June 2022, https://pmc.ncbi.nlm.nih.gov/articles/PMC9794637/
  6. Satya Lakshmi Komarraju, D. Sathyanath, Mandala Sathwik, Shrikanth Muralidharan, “Historical Highlights of Ozone Therapy,” Journal of Pharmacy & BioAllied Sciences, September 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC12564041/.
Kyle Hulbert

Kyle Hulbert is the co-founder and operator at The Longevity Centers of America, which he built alongside Dr. Kosubevsky with the mission to drastically improve the lives of millions of people. Drawing on his own transformation as a patient, he designed the practice around accessibility, affordability, and focus on data-driven regenerative care for individuals who have been underserved by conventional medicine. His background bridges academic rigor and practical application. Hulbert holds bachelor's and master's degrees in business administration, is a doctoral trained researcher, and has carried credentials as a Certified Wellness Coach, Certified Nutrition Coach, and Certified Personal Trainer, all through the National Academy of Sports Medicine, as well as an Integrative Nutrition Coach certification from the Institute for Integrative Nutrition and a Dietary Supplement Specialist designation through the Designs for Health, a trusted leader in science-backed wellness solutions. Hulbert also co-hosts a weekly podcast, "Longevity Unlocked," with Dr. Kosubevsky, translating emerging research on detoxification, hormonal health, and regenerative therapies into real-world discussion to better educate individuals about their health.

About Kyle Hulbert

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